Launch whichever application you installed (Horos or OsiriX).

Download and install Horos or OsiriX as described above.

In this tutorial, however, we will assume you are working with a set of transaxial CT images that cover the orbit at <= 3 mm spacing, and that the images were received on portable media such as a CD, DVD or USB memory stick.

Horos and OsiriX are comprehensive MacOSX DICOM listener clients that can receive images over your local network.

The free OsiriX Lite is a 32-bit application and is not compatible with MacOS 10.15 Catalina and subsequent versions of MacOS which require 64 bit applications.

The paid version of OsiriX is an FDA approved 64 bit application that will run under MacOS 10.15 Catalina.

Download OsiriX and install it on your MacOSX computer.

Horos (version 4.0.0 and greater) is a free 64-bit application that will run under MacOS 10.15 Catalina and subsequent versions of MacOS.

Download Horos and install it on your MacOSX computer.

These 6 reconstructions will be imported into Plaque Simulator and used to measure the size and shape of the eye and, in conjunction with ultrasound images and fundus photos, to determine the tumor size, shape and location within the eye. The user interfaces are nearly identical. Horos (son of Osiris) is derived from the same code base as OsiriX but is free to use.

OsiriX predates Horos but is now a paid, FDA approved product. Other reconstructions of interest are the meridian and coronal planes which intersect the tumor apex. Horos and OsiriX are DICOM listeners and viewers that can manipulate 3-D data sets and export reconstructions of axial, equatorial and sagittal planes which bisect the affected eye as.

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